type of pneumocyte
Features | Type 1 pneumocyte (squamous alveolar cell ) | Type 2 pnemocyte (great alveolar cell, secrerory epithelial cell) |
Numbers | 97% of alveolar surface | 3% of alveolar surface |
Shape | Flat simple squamous epithelial cell | Low cuboidal cell |
Cytoplasm | *little *few organelles -cluster around nucleus -small pnocytic vesicles | *large amount *many organells -large amount of mithocondria, ribosomes,ER, well develop golgi body (characteristic of secrerory cell) |
Nucleus | Flat | Round |
Cell division | *they are differentiated cells. *can’t divide | *can divide. *stem cell of both type. |
Function | -small pnocytic vesicles >assist in turnover of pulmonary surfactant. >removal of small particles from | *secrete pulmonary surfactant -contain phospholipid, proeins and GAG -forms a film over the alveolar epithelium, > which reduce surface tension > prevents collapse of the alveolus during expiration. |
Cell connection | Tight junction( among each other) -prevent leakage of tissue fluid into the alveolar cavity. | Tight junction -with type 1 |
Others | Provide very thin membrane -gaseous exchange occur | *have membrane limited multilamellar bodies( cytosome ) -exhibit many parallel membranes (lamellae) *theor free surface -bulge into the alveolar cavity -covered with short microvilli |
0 comments:
Post a Comment